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IPSS und WPSS Rechner

Definition of the International Prognostic Scoring System (IPSS)

Score 0 0,5 1 1,5 2,0
Medullary blasts (%) 0 - 4 5 - 10 - 11 - 20 21 - 29
Number of Cytopenias1) 0 - 1 2 - 3 - - -
Cytogenetic risk group2) Low Interm. high - -
Risk groups Score
Low risk 0
Intermediate risk I 0,5 - 1
Intermediate risk II 1,5 - 2
High risk ≥ 2,5

1) Platelets < 100.000/µl, Hemoglobin < 10 g/dl, ANC < 1.800/µl
2) low risk = normal Karyotype, 5q-, 20q-, -Y
High risk =complex Karyotype (≥ 3 Anomalien), Chromosom 7-anomalies
Interm. Risk = all other aberrations

 

Definition of WHO adapted Prognostic Scoring System (WPSS)

Score 0 1 2 3
WHO Type RA/RARS/5q- RCMD/RSCMD RAEB I RAEB II
Karoytype risk* low intermediate High -
Transfusion # no yes - -
Risk groups Score
Very low risk 0
Low risk 1
Intermediate risk 2
High risk 3 - 4
Very high risk 5 - 6

*low: normal, -Y, del(5q), del(20q); high: complex, chromosome 7 anomalies; Intermediate: all other abnormalities.
#Transfusion requirement: at least 1 transfusion every 8 weeks over a period of 3 months

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